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College of Arts and Sciences

Dr. Mohamed Eldeeb

Assistant Professor-Biochemistry
Chemistry
Office
SLB Science Laboratory Building 318
Office Hours
Thursday 11 AM- 1 PM or by appointment.
Office Phone
(309) 438-7954office
phone
Email
maeldee@ilstu.eduemail
  • About
  • Awards & Honors
  • Research

Biography

Dr. Eldeeb is an Assistant Professor of Biochemistry at ISU. Dr. Eldeeb obtained his PhD in Biochemistry from the University of Alberta, Canada, where he studied the roles of protein degradation in regulating cell-death signaling. He did his postdoctoral research at McGill University. Dr. Eldeeb's current research aims to mechanistically understand signaling molecules that guide protein degradation, mitochondrial degradation and cell death decisions in response to stress signals.

Current Courses

342.001General Biochemistry I

299.060Independent Honor Study

299.017Independent Honor Study In Chemistry

499.017Independent Research For The Master's Thesis

290.060Research In Biological Sciences

290.017Research in Chemistry

490.017Research In Chemistry

342.001General Biochemistry I

140.015General Chemistry I

299.017Independent Honor Study In Chemistry

499.017Independent Research For The Master's Thesis

290.017Research in Chemistry

490.017Research In Chemistry

Research Interests & Areas

Research in my group aspires to discover and mechanistically understand signaling molecules that regulate protein degradation, mitochondrial degradation and cell death decisions in response to various stress and metabolic signals. Our group asks fundamental questions about the journey of proteins – how do proteins live and die, and how do these processes affect the cell life and death decisions? Our work uses a combination of biochemical, molecular, cellular and genetic approaches to try to answer these questions. Our discoveries help create a better molecular understanding of neurodegenerative diseases and other aging-associated disorders.

Banting Fellowship

CIHR
2020

Basic Research Fellowship

Parkinson Canada
2018

75th Anniversary Scholarship

University of Alberta Faculty of Medicine
2016

Travel Award

American Society of Biochemistry and Molecular Biology
2016

Alberta Innovates-Technology Futures Graduate Scholarship

Alberta Innovates-Technology Futures
2014

Doctoral Recruitment Scholarship

University of Alberta
2011

Lionel B Pett Academic Excellence Graduate Award

University of Alberta
2011

Cairo University Graduate Excellence Award

Cairo University
2010

Zoology Department Excellence Award

Cairo University
2010

Prof. El Halafawy Excellence Award

Cairo University
2008

Journal Article

Eldeeb, M., Fallahi, A., Soumbasis, A., Bayne, A., Trempe, J., & Fon, E. Mitochondrial import stress and PINK1-mediated mitophagy: the role of the PINK1-TOMM-TIMM23 supercomplex.. Autophagy 20.8 (2024): 1903-1905.
Eldeeb, M., Soumbasis, A., & Fon, E. How does mitochondrial import machinery fine-tune mitophagy? Different paths and one destination.. Trends in endocrinology and metabolism: TEM 34.8 (2023): 427-429.
Eldeeb, M., Zhou, W., Esmaili, M., Elgohary, A., Wei, H., & Fahlman, R. N-degron-mediated degradation of the proteolytically activated form of PKC-theta kinase attenuates its pro-apoptotic function.. Cellular signalling 110 (2023): 110830.
Eldeeb, M., Thomas, R., Ragheb, M., Fallahi, A., & Fon, E. Mitochondrial quality control in health and in Parkinson's disease.. Physiological reviews 102.4 (2022): 1721-1755.
Eldeeb, M., Ragheb, M., Soliman, M., & Fahlman, R. Regulation of Neurodegeneration-associated Protein Fragments by the N-degron Pathways.. Neurotoxicity research 40.1 (2022): 298-318.

Other

Eldeeb, M., Hussain, F., & Siddiqi, Z. COVID-19 infection may increase the risk of parkinsonism - Remember the Spanish flu?. Cytokine & growth factor reviews 54 (2020): 6-7.