Dr. Jeremy Driskell
University Professor - Analytical Chemistry
Office
SLB Science Lab Building 215
Office Hours
On Sabbatical / By appt.
Office Phone
Email
- About
- Education
- Awards & Honors
- Selected Research
Current Courses
CHE 299.004 Independent Honor Study In Chemistry
CHE 499.004 Independent Research For The Master's Thesis
CHE 290.004 Research in Chemistry
CHE 490.004 Research In Chemistry
Research Interests & Areas
Research in the Driskell group focuses on the development of novel diagnostic and biological assays by interfacing chemistry, nanomaterials, and biology. Work includes both applied research to develop innovative bioanalytical tools, as well as fundamental research to investigate the mechanism of SERS, antibody-antigen binding kinetics, novel ligands, and protein-nanoparticle interactions.
Post-Doc Chemistry
University of Georgia
Athens, GA
Ph D Analytical Chemistry
Iowa State University
Ames, IA
BS Chemistry
Truman State University
Kirksville, MO
Illinois Science and Technology Coalition (ISTC) Researcher to Know
Illinois Science and Technology Coalition (ISTC)
2025
Outstanding University Researcher
Illinois State University
2025
Named University Professor
Illinois State University
2024
Outstanding College Researcher
CAS
2024
Outstanding Reviewers for Analyst in 2019
Royal Society of Chemistry
2020
Outstanding Reviewers for Analyst in 2018
Royal Society of Chemistry
2019
2016 Emerging Investigator by Analyst
2016
ISU Research Initiative Award to Pre-tenure Faculty
2016
2015 Emerging Investigator by Analytical Methods
2015
DOD-DTRA Young Investigator Award
2013
Grants and Contracts
Enzyme-Mediated Site-Specific Conjugation of Antibodies to Nanoparticles
Jeremy Daniel Driskell.
NIH-NGMS. September 1 2022 - August 31 2025
RUI: Chemically Modified Enzymes to Control Adsorption on Gold Nanoparticles for Enhanced Structure/Function
Jeremy Daniel Driskell.
NSF - MSN. September 1 2022 - August 31 2025
Coupling Raman Spectroscopy with Ambient Sampling, Portable Mass Spectrometry for On-site, High-Throughput Evidence Confirmation on a Single Instrument Platform
Jeremy Daniel Driskell, Christopher Mulligan, Jun-Hyun Kim, Jamie Wieland.
NIJ. January 1 2018 - December 31 2019
RUI: Charge Modified Antibody for Robust and Directional Adsorption onto Gold Nanoparticles
Jeremy Daniel Driskell.
NSF. September 1 2018 - August 31 2021
Flow-through Capture Filters for Enhancing Antibody-Antigen Binding Kinetics
Jeremy Daniel Driskell.
Defense Threat Reduction Agency (DTRA). April 2017 - April 2018
Flow-through Capture Filters for Enhancing Antibody-Antigen Binding Kinetics
Jeremy Daniel Driskell.
Defense Threat Reduction Agency (DTRA). January 17 2015 - January 16 2017
Flow-through Capture Filters for Enhancing Antibody-Antigen Binding Kinetics
Jeremy Daniel Driskell.
Defense Threat Reduction Agency (DTRA). January 1 2013 - January 16 2015
Standardized Immunogold: A systematic investigation into antibody-gold nanoparticle conjugation
Jeremy Daniel Driskell.
New Faculty Iniative Grant. July 1 2012 - June 30 2013
SERS Based Micro-Sensor Arrays for Quantitative miRNAs Detection
Jeremy Daniel Driskell.
National Science Foundation. September 1 2011 - August 31 2014
Intellectual Property
Point of need diagnostic system and method
United States 18/018,968
Jeremy Daniel Driskell, Jun-Hyun Kim.
Journal Article
Oriented Surface Immobilization of Antibodies Using Enzyme-Mediated Site-Specific Biotinylation for Enhanced Antigen-Binding Capacity.
Emily Beitello, Kwame Osei, T Kobulnicky, Faith Breausche, Jon Friesen, Jeremy Daniel Driskell.
Langmuir : the ACS journal of surfaces and colloids, 41 (16), 10576-10585, (2025), 10.1021/acs.langmuir.5c00656
Antibody-Driven Assembly of Plasmonic Core-Satellites to Increase the Sensitivity of a SERS Vertical Flow Immunoassay.
Eunice Ebbah, Anthony Amissah, Jun-Hyun Kim, Jeremy Daniel Driskell.
ACS sensors, 9 (7), 3496-3501, (2024), 10.1021/acssensors.4c01052
Enhanced Sensitivity and Homogeneity of SERS Signals on Plasmonic Substrate When Coupled to Paper Spray Ionization-Mass Spectrometry
Adewale Adehinmoye, Ebenezer Bondzie, Jeremy Daniel Driskell, Christopher Mulligan, Jun-Hyun Kim.
Chemosensors, 12 (9), 175, (2024)
Immobilization of Thiol-Modified Horseradish Peroxidase on Gold Nanoparticles Enhances Enzyme Stability and Prevents Proteolytic Digestion.
Faith Breausche, A Somerlot, J Walder, Kwame Osei, Samuel Okyema, Jeremy Daniel Driskell.
Langmuir : the ACS journal of surfaces and colloids, 40 (27), 13957-13967, (2024), 10.1021/acs.langmuir.4c01180
Controlled Temporal Release of Serum Albumin Immobilized on Gold Nanoparticles.
Tosin Ogunlusi, Jeremy Daniel Driskell.
Langmuir, 39 (10), 3720-3728, (2023), 10.1021/acs.langmuir.2c03429
SERS-based immunoassay on a plasmonic syringe filter for improved sampling and labeling efficiency of biomarkers.
Eunice Ebbah, Anthony Amissah, Jun-Hyun Kim, Jeremy Daniel Driskell.
The Analyst, (2023), 10.1039/d3an01899g
Structure and activity of native and thiolated α-chymotrypsin adsorbed onto gold nanoparticles.
McKenzie Brynne Riley, Evan Strandquist, Chris Weitzel, Jeremy Daniel Driskell.
Colloids and surfaces. B, Biointerfaces, 220, 112867, (2022), 10.1016/j.colsurfb.2022.112867
High-Affinity Points of Interaction on Antibody Allow Synthesis of Stable and Highly Functional Antibody-Gold Nanoparticle Conjugates.
Samuel Okyema, O Awotunde, Tosin Ogunlusi, McKenzie Brynne Riley, Jeremy Daniel Driskell.
Bioconjugate chemistry, 32 (8), 1753-1762, (2021), 10.1021/acs.bioconjchem.1c00261
Probing the Mechanism of Antibody-Triggered Aggregation of Gold Nanoparticles
Samuel Okyema, O Awotunde, Tosin Ogunlusi, McKenzie Brynne Riley, Jeremy Daniel Driskell.
Langmuir, (2021), 10.1021/acs.langmuir.1c00100
Rapid vertical flow immunoassay on AuNP plasmonic paper for SERS-based point of need diagnostics.
Richard Frimpong, W Jang, Jun-Hyun Kim, Jeremy Daniel Driskell.
Talanta, 223 (Pt 2), 121739, (2021), 10.1016/j.talanta.2020.121739
Integrating SERS and PSI-MS with Dual Purpose Plasmonic Paper Substrates for On-Site Illicit Drug Confirmation
Daniel S. Burr, William L. Fatigante, Jemima Lartey, Wongi Jang, Ashley R Stelmack, Noah W. McClurg, Jean Standard, Jamie Wieland, Jun-Hyun Kim, Christopher Mulligan, Jeremy Daniel Driskell.
ANALYTICAL CHEMISTRY, 92 (9), 6676-6683, (2020), 10.1021/acs.analchem.0c00562
Role of Free Thiol on Protein Adsorption to Gold Nanoparticles
Olatunde Awotunde, Samuel Okyem, Rishika Chikoti, Jeremy Daniel Driskell.
LANGMUIR, 36 (31), 9241-9249, (2020), 10.1021/acs.langmuir.0c01550
Antibodies Irreversibly Adsorb to Gold Nanoparticles and Resist Displacement by Common Blood Proteins
Guadalupe Ruiz, Nicki Ryan, Kylie Rutschke, Olatunde Awotunde, Jeremy Daniel Driskell.
Langmuir, (2019), 10.1021/acs.langmuir.9b01900
Sandwiching analytes with structurally diverse plasmonic nanoparticles on paper substrates for surface enhanced Raman spectroscopy
Jemima Lartey, John Harms, Richard Frimpong, Christopher Mulligan, Jeremy Daniel Driskell, Jun-Hyun Kim.
RSC ADVANCES, 9 (56), 32535-32543, (2019), 10.1039/c9ra05399a
pH Impacts the Orientation of Antibody Adsorbed onto Gold Nanoparticles
Guadalupe Ruiz, Kiran Tripathi, Samuel Okyem, Jeremy Daniel Driskell.
BIOCONJUGATE CHEMISTRY, 30 (4), 1182-1191, (2019), 10.1021/acs.bioconjchem.9b00123
Quantifying Bound and Active Antibodies Conjugated to Gold Nanoparticles: A Comprehensive and Robust Approach To Evaluate Immobilization Chemistry
Kiran Tripathi, Jeremy Daniel Driskell.
ACS OMEGA, 3 (7), 8253-8259, (2018), 10.1021/acsomega.8b00591
Asymmetrically Functionalized Antibody-Gold Nanoparticle Conjugates to Form Stable Antigen-Assembled Dimers.
A Mandl, Seth L Filbrun, Jeremy Daniel Driskell.
Bioconjugate chemistry, 28, 38-42, (2017), 10.1021/acs.bioconjchem.6b00459
Chemical modification of antibodies enables the formation of stable antibody-gold nanoparticle conjugates for biosensing
Seth L Filbrun, Alexandra B. Filbrun, Francis L. Lovato, Soon H. Oh, Elizabeth A. Driskell, Jeremy Daniel Driskell.
ANALYST, 142 (23), 4456-4467, (2017), 10.1039/c7an01496a
Structural Characterization and Photoluminescence in the Rare Earth-Free Oxy-Fluoride Anti-Perovskites Sr<sub>3-x
Calvin D Quilty, Maxim Avdeev, Jeremy Daniel Driskell, Eirin Sullivan.
Dalton Transactions, 46, 4055-4065, (2017), 10.1039/c7dt00310b
A fluorescence-based method to directly quantify antibodies immobilized on gold nanoparticles.
Seth L Filbrun, Jeremy Daniel Driskell.
The Analyst, 141 (12), 3851-7, (2016), 10.1039/c6an00193a
SERS immunoassay based on the capture and concentration of antigen-assembled gold nanoparticles.
A Lopez, F Lovato, S H Oh, Yen Lai, Seth L Filbrun, E A Driskell, Jeremy Daniel Driskell.
Talanta, 146, 388-93, (2016), 10.1016/j.talanta.2015.08.065
Rapid Screening of Antibody-Antigen Binding using Dynamic Light Scattering (DLS) and Gold Nanoparticles
Yen Lai, Sunghyu Koo, Oh Hwan Soon, Driskell A. Driskell, Jeremy Daniel Driskell.
Analytical Methods, (2015), 10.1039/C5AY00674K
Controllable and reversible hot spot formation on silver nanorod arrays.
J L Abell, Jeremy Daniel Driskell, Y Zhao.
Chemical communications, 50 (1), 106-8, (2014), 10.1039/c3cc45899g
Effect of hydration on plasmonic coupling of bioconjugated gold nanoparticles immobilized on a gold film probed by surface-enhanced Raman spectroscopy.
Jeremy Daniel Driskell, C G Larrick, C Trunell.
Langmuir, 30 (22), 6309-13, (2014), 10.1021/la500640q
Accelerated surface-enhanced Raman spectroscopy (SERS)-based immunoassay on a gold-plated membrane.
M A Penn, D M Drake, Jeremy Daniel Driskell.
Analytical chemistry, 85 (18), 8609-17, (2013), 10.1021/ac402101r
Monitoring Gold Nanoparticle Conjugation and Analysis of Biomolecular Binding with Nanoparticle Tracking Analysis (NTA) and Dynamic Light Scattering (DLS)
A. E. James, Jeremy Daniel Driskell.
Analyst, 138 (4), 1212-1218, (2013)
Detection and Differentiation of Avian Mycoplasmas by Nanorod Array-Surface-Enhanced Raman Spectroscopy
S. L. Hennigan, Jeremy Daniel Driskell, N. Fergusen, R. A. Dluhy, Y.-P. Zhao, R. A. Tripp, D. C. Krause.
Applied and Environmental Microbiology, 78, 1930-1935, (2012)
Label-free Detection of microRNA Hybridization Using Surface-Enhanced Raman Spectroscopy (SERS) and Least-Squares Analysis
J. Abell, J. Garren, Jeremy Daniel Driskell, R. A. Trip, Y.-P. Zhao.
Journal of the American Chemical Society, 134, 12889-12892, (2012)
Fabrication of Spiropyran-Containing Thin Film Sensors Used for the Simultaneous Identification of Multiple Metal Ions
K. H. Fries, Jeremy Daniel Driskell, G. R. Sheppard, J. Locklin.
Langmuir, 27(19), 12253-12260, (2011)
One-Step Assay for Detecting Influenza Virus Using Dynamic Light Scattering and Gold Nanoparticles
Jeremy Daniel Driskell, C. A. Jone, S. M. Tompkins, R. A. Tripp.
Analyst, 136, 3083-3090, (2011)
Label-free SERS detection of microRNA based on affinity for an unmodified silver nanorod array substrate.
Jeremy Daniel Driskell, R A Tripp.
Chemical communications (Cambridge, England), 46 (19), 3298-300, (2010), 10.1039/c002059a
Rapid and sensitive detection of rotavirus molecular signatures using surface enhanced Raman spectroscopy.
Jeremy Daniel Driskell, Y Zhu, C D Kirkwood, Y Zhao, R A Dluhy, R A Tripp.
PloS one, 5 (4), e10222, (2010), 10.1371/journal.pone.0010222
Rotationally induced hydrodynamics: fundamentals and applications to high-speed bioassays.
G Wang, Jeremy Daniel Driskell, A A Hill, E J Dufek, R J Lipert, M D Porter.
Annual review of analytical chemistry (Palo Alto, Calif.), 3, 387-407, (2010), 10.1146/annurev.anchem.111808.073644
Spectroscopic analysis of metal ion binding in spiropyran containing copolymer thin films.
K H Fries, Jeremy Daniel Driskell, S Samanta, J Locklin.
Analytical chemistry, 82 (8), 3306-14, (2010), 10.1021/ac1001004
Control of antigen mass transport via capture substrate rotation: binding kinetics and implications on immunoassay speed and detection limits.
G Wang, Jeremy Daniel Driskell, M D Porter, R J Lipert.
Analytical chemistry, 81 (15), 6175-85, (2009), 10.1021/ac900704t
Fabrication and characterization of a multiwell array SERS chip with biological applications.
J L Abell, Jeremy Daniel Driskell, R A Dluhy, R A Tripp, Y P Zhao.
Biosensors & bioelectronics, 24 (12), 3663-70, (2009), 10.1016/j.bios.2009.05.039
Quantitative surface-enhanced Raman spectroscopy based analysis of microRNA mixtures.
Jeremy Daniel Driskell, O M Primera-Pedrozo, R A Dluhy, Y Zhao, R A Tripp.
Applied spectroscopy, 63 (10), 1107-14, (2009), 10.1366/000370209789553183
Identification and classification of respiratory syncytial virus (RSV) strains by surface-enhanced Raman spectroscopy and multivariate statistical techniques.
S Shanmukh, L Jones, Y P Zhao, Jeremy Daniel Driskell, R A Tripp, R A Dluhy.
Analytical and bioanalytical chemistry, 390 (6), 1551-5, (2008), 10.1007/s00216-008-1851-0
Rapid microRNA (miRNA) detection and classification via surface-enhanced Raman spectroscopy (SERS).
Jeremy Daniel Driskell, A G Seto, L P Jones, S Jokela, R A Dluhy, Y P Zhao, R A Tripp.
Biosensors & bioelectronics, 24 (4), 923-8, (2008), 10.1016/j.bios.2008.07.060
Surface-enhanced Raman scattering immunoassays using a rotated capture substrate.
Jeremy Daniel Driskell, J M Uhlenkamp, R J Lipert, M D Porter.
Analytical chemistry, 79 (11), 4141-8, (2007), 10.1021/ac0701031
Control of antigen mass transfer via capture substrate rotation: an absolute method for the determination of viral pathogen concentration and reduction of heterogeneous immunoassay incubation times.
Jeremy Daniel Driskell, K M Kwarta, R J Lipert, A Vorwald, J D Neill, J F Ridpath, M D Porter.
Journal of virological methods, 138 (1-2), 160-9, (2006), 10.1016/j.jviromet.2006.08.011
Detection of viruses: atomic force microscopy and surface enhanced Raman spectroscopy.
M D Porter, Jeremy Daniel Driskell, K M Kwarta, R J Lipert, J D Neill, J F Ridpath.
Developments in biologicals, 126, 31-9; discussion 323, (2006)
Labeled gold nanoparticles immobilized at smooth metallic substrates: systematic investigation of surface plasmon resonance and surface-enhanced Raman scattering.
Jeremy Daniel Driskell, R J Lipert, M D Porter.
The journal of physical chemistry. B, 110 (35), 17444-51, (2006), 10.1021/jp0636930
Low-level detection of viral pathogens by a surface-enhanced Raman scattering based immunoassay.
Jeremy Daniel Driskell, K M Kwarta, R J Lipert, M D Porter, J D Neill, J F Ridpath.
Analytical chemistry, 77 (19), 6147-54, (2005), 10.1021/ac0504159
The alpha-effect in methyl transfers from S-methyldibenzothiophenium fluoroborate to substituted N-methylbenzohydroxamates.
K R Fountain, C J Felkerson, Jeremy Daniel Driskell, B D Lamp.
The Journal of organic chemistry, 68 (5), 1810-4, (2003), 10.1021/jo0206263
Other
Outstanding Reviewers for Analyst in 2019
Hugh Byrne, Lingxin Chen, Yu-Chung Chang, Jeremy Daniel Driskell, Ning Gan, Hideaki Hisamoto, Juewen Liu, Francis Martin, Muhammad Shiddiky, Chun-yang Zhang.
ROYAL SOC CHEMISTRY, 145 (12), 4068-4068, (2020), 10.1039/d0an90052d
Presentations
Enzyme-mediated site-specific immobilization of antibody onto gold nanoparticles
Jeremy Daniel Driskell.
SciX, Cincinnati, OH, October 8, 2025
SERS Vertical Flow Immunoassay Leveraging Antibody-Directed Assembly of Plasmonic Particles
Jeremy Daniel Driskell.
SciX, Cincinnati, OH, October 7, 2025
SERS-based Vertical Flow Assay Exploiting Plasmonic Paper and Antibody-Directed Assembly of Plasmonic Core-Satellites for Point of Care Diagnostics
Jeremy Daniel Driskell.
ACS Spring 2025 National Meeting, San Diego, CA, March 26, 2025
Structure and Activity of Thiolated Enzymes Adsorbed onto Gold Nanoparticles to form Highly Functional Bioconjugates
Jeremy Daniel Driskell.
ACS Fall 2023 National Meeting, San Francisco, CA, August 17, 2023
SERS-based Vertical Flow Assay on Plasmonic Paper for Point of Care Diagnostics
Jeremy Daniel Driskell.
SciX, Cincinnati, OH, October 3, 2022
Adsorption Behavior of Chemically/Charged Modified Antibody on Gold Nanoparticles
Jeremy Daniel Driskell.
ACS Spring 2022 National Meeting, San Diego, CA, March 21, 2022
Investigating the Stability and Orientation of Antibody Adsorbed onto Gold Nanoparticles
Jeremy Daniel Driskell.
ACS Spring 2021 National Meeting, Philadelphia, PA, March 23, 2021
Coupling Raman Spectroscopy with Ambient Sampling, Portable Mass Spectrometry for On-site, High-Throughput Evidence Confirmation on a Single Instrumental Platform
Jeremy Daniel Driskell.
American Academy of Forensic Sciences (AAFS) Annual Meeting, Anaheim, CA, February 18, 2020
Integrated SERS-PSI-MS Platform Using Gold Nanoparticle-Embedded Paper for Trace Detection of Illegal Drugs
Jeremy Daniel Driskell, C. Mulligan, J.-H. Kim, W. Fatigante, D. Burr, J. Lartey.
SciX, Palm Springs, CA, October 14, 2019
Investigating Antibody-Gold Nanoparticle Adsorption Dynamics to Optimize Conjugates for Biosensing
Jeremy Daniel Driskell.
SciX, Palm Springs, CA, October 14, 2019
Investigating Adsorption Dynamics of Serum Proteins onto Gold Nanoparticles
Guadalupe Ruiz, Nicki Ryan, Jeremy Daniel Driskell.
ISU Research Symposium, Normal, IL, April 5, 2019
Optimization of Plasmonic Papers for Two-Tiered Drug Analysis on a Portable, SERS-PSI-MS Platform
D. Burr, J. Harms, W. Fatigante, J.-H. Kim, C. Mulligan, Jeremy Daniel Driskell.
ISU Research Symposium, Normal, IL, April 5, 2019
Functionalized Gold Nanoparticles for Biosensing with Surface-Enhanced Raman Scattering (SERS)
Jeremy Daniel Driskell.
North Park University, North Park, IL, April 5, 2019
Towards on-site drug evidence confirmation using ambient sampling, portable mass spectrometry
C. Mulligan, W. Fatigante, A. Stelmack, D. Burr, J. Harms, J.-H. Kim, Jeremy Daniel Driskell, J. Wieland.
257th ACS National Meeting & Exposition, Orlando, FL, April 2, 2019
Impact of pH on the Orientation of Antibody Adsorbed onto Gold Nanoparticles
Jeremy Daniel Driskell.
257th ACS National Meeting & Exposition, Orlando, FL, March 31, 2019
Investigating Adsorption Dynamics of Serum Proteins onto Gold Nanoparticles
Guadalupe Ruiz, Nicki Ryan, Jeremy Daniel Driskell.
257th ACS National Meeting & Exposition, Orlando, FL, March 31, 2019
Sandwich structure of plasmonic paper for surface enhanced Raman spectroscopy
J. Harms, D. Burr, W. Fatigante, C. Mulligan, Jeremy Daniel Driskell, J.-Hy. Kim.
257th ACS National Meeting & Exposition, Orlando, FL, March 31, 2019
Optimization of Plasmonic Papers for Two-Tiered Drug Analysis on a Portable, SERS-PSI-MS Platform
D. Burr, J. Harms, W. Fatigante, J.-H. Kim, C. Mulligan, Jeremy Daniel Driskell.
Pittcon, Philadelphia, PA, March 18, 2019
An Analytical Strategy to Evaluate and Optimize Antibody-Gold Nanoparticle Conjugation Chemistry
Jeremy Daniel Driskell.
SciX, Atlanta, GA, October 23, 2018
Coupling SERS and ambient ionization mass spectrometry with plasmonic paper for on-site, trace analysis of illicit drugs
Jeremy Daniel Driskell.
SciX, Atlanta, GA, October 23, 2018
Investigating Antibody Adsorption Dynamics onto Gold Nanoparticles to Form Stable Conjugates for Analysis of Biological Fluids
Jeremy Daniel Driskell.
255th ACS National Meeting & Exposition, New Orleans, LA, March 20, 2018
SERS Detection of Avian Influeznza Virus H3 Subtypes using Functionalized Gold Nanoparticles
Jeremy Daniel Driskell.
Pittcon, Orlando, FL, March 1, 2018
Functionalized Gold Nanoparticles for Biosensing with Surface-Enhanced Raman Scattering (SERS)
Jeremy Daniel Driskell.
Illinois Wesleyan University, Bloomington, IL, November 17, 2017
Flow-through Capture Filters for Enhancing Antibody-Antigen Binding Kinetics
Jeremy Daniel Driskell.
Defense Threat Reduction Agency Annual Technical Review, Washington D.C., June 21, 2017
Functionalized Gold Nanoparticles for Biosensing with Surface-Enhanced Raman Scattering (SERS)
Jeremy Daniel Driskell.
Northern Kentucky University, Covington, KY, April 12, 2017