Professor Gregory Ferrence

Yawson, Gideon K.; Will, Mark F.; Huffman, Samantha E.; Strandquist, Evan T.; Bothwell, Paige J.; Oliver, Ethan B.; Platt, David C.; Apuzzo, C. Fiore; Weitzel, Christopher S.; Jones, Marjorie A.; Ferrence, Gregory M.; Hamaker, Christopher G.; Webb, Michael I. “A Dual-Pronged Approach: A Ruthenium(III) Complex That Modulates Amyloid-β Aggregation and Disrupts Its Formed Aggregates” Inorganic Chemistry, 2022, 61, 2733-2744.

Amason, Edith K.; Jones, Meredith H.; Keuk, Channita, Ferrence, Gregory M.; Bachman, Robert E.; Joslin, Evan E. “Synthesis and characterization of the complete series of chlorine substituted cobalt acetylacetonate complexes – [Co(acac)_x(acac-Cl)₃-x], x = 0-3,” Polyhedron 2021, 201(115188), 1-7, DOI: 10.1016/j.poly.2021.115188.

Wall, Brendan J.^‡; Will, Mark F.^‡; Yawson, Gideon K.; Bothwell, Paige J.; Platt, David C.; Apuzzo, C. Fiore; Jones, Marjorie A.; Ferrence, Gregory M.; Webb, Michael I. “The Importance of Hydrogen Bonding: Structure-Activity Relationships of Ruthenium(III) Complexes for Alzheimer’s Disease Therapy with Pyridine-based Ligands” Journal of Medicinal Chemistry 2021, 64, 10124-10138 (^‡ = each author contributed equally to this work)

Yawson, Gideon K.; Huffman, Samantha E.; Fisher, Samuel S.; Bothwell, Paige J.; Platt, David C.; Jones, Marjorie A.; Ferrence, Gregory M.; Hamaker, Christopher G.; Webb, Michael I. “Ruthenium(III) complexes with imidazole ligands that modulate the aggregation of the amyloid-β peptide via hydrophobic interactions,” Journal of Inorganic Biochemistry 2021, 214(111303), 1-10. DOI: 10.1016/j.jinorgbio.2020.111303.

Grabowski, Jacob P.; Ferrence, Gregory M.; Mitchell T. Andrew “Efforts toward the total synthesis of (±)-toxicodenane A utilizing an oxidopyrylium-based [5+2] cycloaddition of a silicon-tethered BOC-pyranone,” Tetrahedron Letters 2020, 61(36), 152324. DOI: 10.1016/j.tetlet.2020.152324.

Rokey, Samantha N.; Simanis, Justin A.; Law, Chunyin M.; Pohani, Shilpa; Willens Behrends, Samantha; Bulandr, Jacob J.; Ferrence, Gregory M.; Goodell, John R.; Andrew Mitchell, T. “Intramolecular asymmetric oxidopyrylium-based [5 + 2] cycloadditions,” Tetrahedron Letters 2020, 61(41), 152377. DOI: 10.1016/j.tetlet.2020.152377.

Interactive X-ray link: YUTPAG and YUTPEK | D. L. Gerlach, I. Nieto, C. J. Herbst-Gervasoni, G. M. Ferrence, M. Zeller and E. T. Papish "Crystal structures of bis- and hexakis[(6,6'-di-hydroxybipyridine)copper(II)] nitrate coordination complexes," Acta Crystallographica Section E: Crystallographic Communications 2015, E71, 1447-1443, DOI: 10.1107/S205698901502037X link.

Interactive X-ray links: JUTVOL, JUTVUR and JUTWAY |L. M. Stateman, G. M. Ferrence and T. D. Lash “Rhodium(III) azuliporphyrins," Organometallics 2015, 34, 3842-3848, DOI: 10.1021/acs.organomet.5b00433 link.

Interactive X-ray links: QUSDUF, QUSDIT and QUSDOZ | T. D. Lash, D. A. Colby, J. A. El-Beck, D. I. AbuSalim and G. M. Ferrence “Preparation, structural characterization, assessment of potential antiaromaticity and metalation of 21-oxyazuliporphyrins," Inorganic Chemistry 2015, 54, 9174-9187, DOI: 10.1021/acs.inorgchem.5b01587 link.

Interactive X-ray links: XUWGON and XUWGUT | T. D. Lash, D. I. AbuSalim and G. M. Ferrence "adj-Dicarbachlorin, the first example of a free base carbaporphyrinoid system with an internal methylene unit," Chemical Communications 2015, 51, 15952-15955, DOI: 10.1039/C5CC06890H link.

Interactive X-ray link: GUNTOA | C. A. Olson, C. E. Shaner, S.C. Roche, G. M. Ferrence, and T. A. Mitchell "Hexahydro-1Hisoindolinone-like scaffolds from electronically deactivated and sterically hindered dinenes: Synthesis in the context of Muironolide A," Synthesis 2015, 47(18), 2756-2766, DOI: 10.1055/s-0034-1380221 link.

Interactive X-ray link: TUJNIX | G. M. Ferrence and J. L. Kocher "Crystal structure of 3-methyl-5-tri­methyl­silyl-1H-pyrazole," Acta Crystallographica Section E: Crystallographic Communications, 2015, E71, 0397, DOI: 10.1107/S2056989015008567 link.

Interactive X-ray link: YOTHOG | and Interactive X-ray link: YOTHUM | A. Nourmahnad, M. D. Smith, M. Zeller, G. M. Ferrence, J. Schrier and A. J. Norquist “Role of noncovalent interactions in vanadium tellurite chain connectivities,” Inorganic Chemistry 2015, 54, 694-703, DOI: 10.1021/ic502753e link.

Interactive X-ray link: PUCREM | S. C. Fosu , G. M. Ferrence and T. D. Lash "Synthesis and metalation of dimethoxybenziporphyrins, thiabenziporphyrins and dibenziporphyrins," Journal of Organic Chemistry, 2014, 79, 11061-11074, DOI: 10.1021/jo502063w link.

Interactive X-ray links: SOTZOS, SOTZUY, SOVMUN and SOVNAU | Ruoshi Li , Aaron D. Lammer , Gregory M. Ferrence , and Timothy D. Lash, "Synthesis, structural characterization, aromatic properties and metalation of neo-confused porphyrins, a newly discovered class of porphyrin isomers," Journal of Organic Chemistry, 2014, 79, 4078-4093, DOI: 10.1021/jo500580e link.

Interactive X-ray links: CILTAU and CILTEY | Timothy D. Lash, Jessica A. El-Beck, Gregory M. Ferrence, "Synthesis, structural characterization and reactivity of heteroazuliporphyrins," Organic and Biomolecular Chemistry, 2014, 12, 316, DOI: 10.1039/C3OB41992D link.

Interactive X-ray links: TIXHIT, TIWTIE, TIWTOK, TIWTUQ, TIWVAY, TIWVEC, TIWVIG, TIWVOM, TIWVUS, TIWWAZ, TIWWED, TIWWIH, TIWWON, and TIWWUT | Michael R. Azar , Thaddeus T. Boron , III, Jacob C. Lutter , Connor I. Daly , Kelcie A. Zegalia, Ruthairat Nimthong , Gregory M. Ferrence , Matthias Zeller , Jeff W. Kampf , Vincent L. Pecoraro , and Curtis M. Zaleski, "Controllable formation of heterotrimetallic coordination compounds: Systematically incorporating lanthanide and alkali metal ions into the manganese 12-metallacrown-4 framework," Inorganic Chemistry, 2014, 53, 1729, DOI: 10.1021/ic402865p link.

Interactive X-ray link: RIYGUD | Deyaa I. AbuSalim , Gregory M. Ferrence , and Timothy D. Lash, "Synthesis of an adj-dicarbaporphyrin and the formation of an unprecedented tripalladium sandwich complex," Journal of the American Chemical Society, 2014, 136, 6763, DOI: 10.1021/ja502795x link.

Interactive X-ray link: VIHQOU | Courtnay E. Shaner, Gregory M. Ferrence, T. Andrew Mitchell, "Synthetic efforts toward the isoindolinone core of muironolide A," Synlett, 2013, 24, 1861, DOI: 10.1055/s-0033-1339327 link.

Interactive X-ray link: PIGPAY | Ruoshi Li, Gregory M. Ferrence, Timothy D. Lash, "Synthesis of a neo-confused porphyrin and an unusual dihydroporphyrin derivative," Chemical Communications, 2013, 49, 7537, DOI: 10.1039/C3CC44248A link.

Interactive X-ray link: LIQJIG | Timothy D. Lash, Ashley M. Toney, Kylie M. Castans, and Gregory M. Ferrence, "Synthesis of benziporphyrins and heterobenziporphyrins and an assessment of the diatropic characteristics of the protonated species," Journal of Organic Chemistry, 2013, 78, 9143, DOI: 10.1021/jo401365p link.

Interactive X-ray links: HIKTIG, HIKTOM, HIKTUS, HIKVAA, HIKVOO, HIKVUU and HIKWAB | Jacob H. Koffer, Jacob H. Olshansky, Matthew D. Smith, Kristen J. Hernandez, Matthias Zeller, Gregory M. Ferrence, Joshua Schrier, and Alexander J. Norquist, "Formation principles for templated vanadium selenite oxalates," Crystal Growth and Design, 2013, 13, 4504, DOI: 10.1021/cg400992q link.

Interactive X-ray link: NEQRIM | K. A. Slater, B. Andersh, E. B. Flint, G. M. Ferrence, "6-Phenyl­oxane-2,4-dione," Acta Crystallographica Section E: Structure Reports Online, 2013, 69, o69, DOI: 10.1107/S1600536812049781 link.

Interactive X- ray links: BEJGUU and BEJHAB | T. D. Lash, A. D. Lammer, G. M. Ferrence, "Two-step synthesis of stable dioxadicarbaporphyrins from bis(3-indenyl)methane," Angewandte Chemie, International Edition, 2012, 51, 10871, DOI: 10.1002/anie.201206385 link.

Interactive X-ray link: SELVOW | T. D. Lash, K. Pokharel, M. Zeller, G. M. Ferrence, "Iridium(III) azuliporphyrins," Chemical Communications, 2012, 48, 11793, DOI: 10.1039/c2cc37104a link.

Interactive X-ray link: UCIFET | T. D. Lash, A. M. Young, J. M. Rasmussen, G. M. Ferrence, "Naphthiporphyrins," Journal of Organic Chemistry, 2011, 76, 5636, DOI: 10.1021/jo200622s link.

Interactive X-ray link: XANVEP | T. D. Lash, K. Miyake, Linlin Xu, G. M. Ferrence, "Synthesis of a series of aromatic benziporphyrins and heteroanalogues via tripyrrane-like intermediates derived from resorcinol and 2-methylresorcinol," Journal of Organic Chemistry, 2011, 76, 6295, DOI: 10.1021/jo201098c link.

Interactive X-ray link: ECAFIZ | T. D. Lash, A. D. Lammer, G. M. Ferrence, "Neo-confused porphyrins, a new class of porphyrin isomers," Angewandte Chemie, International Edition, 2011, 50, 9718, DOI: 10.1002/anie.201104826 link.

Interactive X-ray link: UNONER | D. Crawford, A. K. Hofer, K. L. Edler, G. M. Ferrence, "Bis(3,5-dimethyl-1H-pyrazole-κN²)silver(I) hexafluoridoantimonate," Acta Crystallographica Section E: Structure Reports Online, 2011, 67, m496, DOI: 10.1107/S1600536811010567 link.

Gary M. Battle, Frank H. Allen, Gregory M. Ferrence, "Teaching three-dimensional structural chemistry using crystal structure databases. 3. The Cambridge Structural Database System: Information content and access software in educational applications," Journal of Chemical Education, 2011, 88, 891, DOI: 10.1021/ed1011019 link.

Gary M. Battle, Frank H. Allen, Gregory M. Ferrence, "Teaching three-dimensional structural chemistry using crystal structure databases. 4. Examples of discovery-based learning using the complete Cambridge Structural Database," Journal of Chemical Education, 2011, 88, 886, DOI: 10.1021/ed1011025 link.

Interactive X- ray links: QUHMAJ, QUHLUC | Shawn R. Hitchcock, Melissa A. Dean, Christopher J. Kelley, Kate L. Edler, Gregory M. Ferrence, "Synthesis and X-ray crystal structures of chiral, nonracemic 5,6-dihydro-4H-1,3,4-oxadiazines," Journal of Heterocyclic Chemistry, 2010, 47, 982, DOI: 10.1002/jhet.402 link.

Interactive X-ray link: CUZVUP | S. Banerjee, G. M. Ferrence, S. R. Hitchcock, "Catalytic asymmetric addition of diethylzinc to aldehydes via chiral, non-racemic β-hydroxy and β-methoxy salicylhydrazone catalysts," Tetrahedron:Asymmetry, 2010, 21, 837, DOI: 10.1016/j.tetasy.2010.04.021 link.

Interactive X-ray link: GUZPUN | H. Boedigheimer, G. M. Ferrence, T. D. Lash, "Porphyrin on a half-shell! Synthesis and characterization of corannulenenoporphyrins," Journal of Organic Chemistry, 2010, 75, 2518, DOI: 10.1021/jo902592u link.

Interactive X-ray link: TUZNUY | T. D. Lash, S. A. Jones, G. M. Ferrence, "Synthesis and characterization of tetraphenyl-21,23-dideazaporphyrin. The best evidence yet that porphyrins really are the [18]annulenes of nature," Journal of the American Chemical Society, 2010, 132, 12786, DOI: 10.1021/ja105146a link.

Interactive X- ray links: ITUCIK, ITUCOQ, ITUCUW and ITUDAD | P. Jain, G. M. Ferrence, T. D. Lash, "Preparation of furan and thiophene-derived fulvene dialdehydes: synthesis and structural characterization of a 22-oxa-21-carbaporphyrin and a related palladium(II) organometallic complex," Journal of Organic Chemistry, 2010, 75, 6563, DOI: 10.1021/jo101310m link.

Gary M. Battle, Frank H. Allen, Gregory M. Ferrence, "Teaching three-dimensional structural chemistry using crystal structure databases. 1. An interactive web-accessible teaching subset of the Cambridge Structural Database," Journal of Chemical Education, 2010, 87, 809, DOI: 10.1021/ed100256k link.

Gary M. Battle, Frank H. Allen, Gregory M. Ferrence, "Teaching three-dimensional structural chemistry using crystal structure databases. 2. Teaching units that utilize an interactive web-accessible subset of the Cambridge Structural Database," Journal of Chemical Education, 2010, 87, 813, DOI: 10.1021/ed100257t link.

Gary M. Battle, Gregory M. Ferrence, Frank H. Allen, "Applications of the Cambridge Structural Database in chemical education," Journal of Applied Crystallography, 2010, 43, 1208, DOI: 10.1107/S0021889810024155 link.

Z. Zhang, G. M. Ferrence and T. D. Lash, “adj-Diazuliporphyrins, a new family of dicarbaporphyrinoids with unprecedented mesoionic characteristics”, Organic Letters 2009, 11, 101-104.

Z. Zhang, G. M. Ferrence and T. D. Lash, “MacDonald-type reactions using bis-acrylaldehydes: synthesis of an expanded sapphyrin and vinylogous hexaphyrins”, Organic Letters 2009, 11, 1249-1252.

T. D. Lash, A. M. Young, A. L. Von Ruden and G. M. Ferrence, “Adding to the confusion! Synthesis and metalation of pyrazole analogues of the porphyrins”, Chemical Communications 2008, 6309-6311.

T. D. Lash, J. A. El-Beck and G. M. Ferrence, “Syntheses and reactivity of meso-unsubstituted azuli-porphyrins derived from 6-tert-butyl- and 6-phenylazulene”, Journal of Organic Chemistry 2007, 72, 8402-8415.

T. D. Lash, J. T. Szymanski and G. M. Ferrence, “Tetraaryldimethoxybenziporphyrins. At the edge of carbaporphyrinoid aromaticity”, Journal of Organic Chemistry 2007, 72, 6481-6492.

T. D. Lash, K. Pokharel, J. M. Serling, V. R. Yant and G. M. Ferrence, “Aromatic and nonaromatic pyriporphyrins”, Organic Letters 2007, 9, 2863-2866.

L. Xu, G. M. Ferrence and T. D. Lash, “[22]Porphyrin-(3.1.1.3), a new vinylogous expanded porphyrin system”, Organic Letters 2006, 8, 5113-5116.

T. D. Lash, D. A. Colby, S. R. Graham, G. M. Ferrence and L. F. Szczepura, “Organometallic Chemistry of Azuliporphyrins: Synthesis, Spectroscopy, Electrochemistry and Structural Characterization of Nickel(II), Palladium(II) and Platinum(II) Complexes of Azuliporphyrins”, Inorganic Chemistry 2003, 42, 7326-7338.

Gregory Ferrence, "Exploring ethics in the laboratory," inChemistry, 2013, Nov/Dec, 3, digital reprint: free reprint link.